InterDILI: interpretable prediction of drug-induced liver injury through permutation feature importance and attention mechanism

Abstract Safety is one of the important factors constraining the distribution of clinical drugs on the market. Drug-induced liver injury (DILI) is the leading cause of safety problems produced by drug side effects. Therefore, the DILI risk of approved drugs and potential drug candidates should be as...

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Bibliographic Details

Published in:	Journal of Cheminformatics
Main Authors:	Soyeon Lee, Sunyong Yoo
Format:	Article
Language:	English
Published:	BMC 2024-01-01
Subjects:	Attention mechanism Drug-induced liver injury Feature importance Hepatotoxicity In silico prediction
Online Access:	https://doi.org/10.1186/s13321-023-00796-8