Modeling glioblastoma heterogeneity as a dynamic network of cell states

Abstract Tumor cell heterogeneity is a crucial characteristic of malignant brain tumors and underpins phenomena such as therapy resistance and tumor recurrence. Advances in single‐cell analysis have enabled the delineation of distinct cellular states of brain tumor cells, but the time‐dependent chan...

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Bibliographic Details

Published in:	Molecular Systems Biology
Main Authors:	Ida Larsson, Erika Dalmo, Ramy Elgendy, Mia Niklasson, Milena Doroszko, Anna Segerman, Rebecka Jörnsten, Bengt Westermark, Sven Nelander
Format:	Article
Language:	English
Published:	Springer Nature 2021-09-01
Subjects:	cell state cellular barcoding patient‐derived brain tumor cells single‐cell lineage tracing time‐dependent computational models
Online Access:	https://doi.org/10.15252/msb.202010105