Major depressive disorder plays a vital role in the pathway from gastroesophageal reflux disease to chronic obstructive pulmonary disease: a Mendelian randomization study

Background: Observational studies have shown a bidirectional association between chronic obstructive pulmonary disease (COPD) and gastroesophageal reflux disease (GERD), but it is not clear whether this association is causal. In our previous study, we found that depression was a hot topic of researc...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Menglong Zou, Wei Zhang, Lele Shen, Yin Xu, Ying Zhu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	instrumental variables Mendelian randomization gastroesophageal reflux disease major depressive disorder chronic obstructive pulmonary disease causal effect
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2023.1198476/full