FCRLs and atypical transcriptional pattern in tumor infiltrating B cells from lung and renal cancer

Advances in high-dimensional flow cytometry and single-cell RNA sequencing (scRNA-seq) have enhanced our understanding of the heterogeneity of tumor-infiltrating B cells (TIBs). Subpopulations of TIBs exhibit diverse, sometimes opposing roles in tumor control, influenced by surface molecule, cytokin...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Ekaterina A. Bryushkova, Evgenii V. Shchoka, Daniil K. Lukyanov, Marina B. Gikalo, Natalya Mushenkova, Konstantin K. Laktionov, Alexey M. Kazakov, Oybek A. Khalmurzaev, Vsevolod B. Matveev, Dmitriy M. Chudakov, Ekaterina O. Serebrovskaya
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	tumor infiltrating B cells surface IgA lung adenocarcinoma FcRL4 RUNX2
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1587088/full