SunTag-PE: a modular prime editing system enables versatile and efficient genome editing

Abstract Prime editing (PE) holds tremendous potential in the treatment of genetic diseases because it can install any desired base substitution or local insertion/deletion. However, the full-length PE effector size (6.3-kb) is beyond the packaging capacity of adeno-associated virus (AAV), hindering...

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書誌詳細

出版年:	Communications Biology
主要な著者:	Jiashuo Liu, Jingjing Zhang, Tingting Zhao, Mengya Zhao, Min Su, Ye Chen, Zheying Huang, Yuyan Wang, Chaoyue Zhong, Zheng Hu, Ping Zhou, Rui Tian, Dan He
フォーマット:	論文
言語:	英語
出版事項:	Nature Portfolio 2025-03-01
オンライン･アクセス:	https://doi.org/10.1038/s42003-025-07893-4