Interleukin-6 and Interleukin-8 Regulate STAT3 Activation Migration/Invasion and EMT in Chrysophanol-Treated Oral Cancer Cell Lines

The tumor microenvironment plays a critical role in the control of metastasis. The epithelial–mesenchymal transition (EMT) is strongly associated with tumor metastasis, and consists of several protein markers, including E-cadherin and vimentin. We discovered that chrysophanol causes oral cancer cell...

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Bibliographic Details

Published in:	Life
Main Authors:	Po-Chih Hsu, Yi-Hsuan Chen, Ching-Feng Cheng, Chan-Yen Kuo, Huey-Kang Sytwu
Format:	Article
Language:	English
Published:	MDPI AG 2021-05-01
Subjects:	chrysophanol IL-6 IL-8 EMT migration invasion
Online Access:	https://www.mdpi.com/2075-1729/11/5/423