Histologically resolved multiomics enables precise molecular profiling of human intratumor heterogeneity.
Both the composition of cell types and their spatial distribution in a tissue play a critical role in cellular function, organ development, and disease progression. For example, intratumor heterogeneity and the distribution of transcriptional and genetic events in single cells drive the genesis and...
| Published in: | PLoS Biology |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-07-01
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| Online Access: | https://doi.org/10.1371/journal.pbio.3001699 |