Effect of Pirfenidone on Vascular Proliferation, Inflammation and Fibrosis in an Abdominal Adhesion Rat Model

Aim: To study the efficacy of pirfenidone for prevention of postoperative adhesion formation in an adhesion rat model. Materials and Methods: Eighteen female Wistar rats were subjected to right-sided parietal peritoneum and right uterine horn adhesion model. Rats were randomized into three groups: g...

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Bibliographic Details

Published in:	Journal of Investigative Surgery
Main Authors:	Pinar Solmaz Hasdemir, Mahmud Ozkut, Tevfik Guvenal, Melis Aylin Uner, Esat Calik, Semra Oruc Koltan, Faik Mumtaz Koyuncu, Kemal Ozbilgin
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2017-01-01
Subjects:	adhesion fibrosis interleukin-17 pirfenidone rat transforming growth factor-β
Online Access:	http://dx.doi.org/10.1080/08941939.2016.1215578