CD11b Regulates Fungal Outgrowth but Not Neutrophil Recruitment in a Mouse Model of Invasive Pulmonary Aspergillosis

ß2 integrin receptors consist of an alpha subunit (CD11a-CD11d) and CD18 as the common beta subunit, and are differentially expressed by leukocytes. ß2 integrins are required for cell-cell interaction, transendothelial migration, uptake of opsonized pathogens, and cell signaling processes. Functiona...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Daniel Teschner, Anna Cholaszczyńska, Frederic Ries, Hendrik Beckert, Matthias Theobald, Stephan Grabbe, Markus Radsak, Matthias Bros
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-02-01
Subjects:	Aspergillus fumigatus pneumonia β2 integrins CD11b complement receptor 3 polymorphonuclear neutrophils
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2019.00123/full