Co-delivery of polyphyllin II and IR780 PLGA nanoparticles induced pyroptosis combined with photothermal to enhance hepatocellular carcinoma immunotherapy

Abstract The clinical efficacy of immunotherapy for hepatocellular carcinoma (HCC) is significantly limited by the low immunogenicity of the tumor. Recent studies have revealed that both pyroptosis and photothermal therapy can effectively induce tumor immunogenic cell death (ICD) in liver cancer cel...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Huating Huang, Jing Fu, Hulinyue Peng, Yuanyuan He, Aqian Chang, Huizhong Zhang, Yang Hao, Xiaohan Xu, Shiman Li, Jingxia Zhao, Jian Ni, Xiaoxv Dong
Format:	Article
Language:	English
Published:	BMC 2024-10-01
Subjects:	Pyroptosis Photothermal Aptamer Immunotherapy
Online Access:	https://doi.org/10.1186/s12951-024-02887-6