Activation of STAT3-mediated ciliated cell survival protects against severe infection by respiratory syncytial virus

Respiratory syncytial virus (RSV) selectively targets ciliated cells in human bronchial epithelium and can cause bronchiolitis and pneumonia, mostly in infants. To identify molecular targets of intervention during RSV infection in infants, we investigated how age regulates RSV interaction with the b...

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發表在:	The Journal of Clinical Investigation
Main Authors:	Caiqi Zhao, Yan Bai, Wei Wang, Gaurang M. Amonkar, Hongmei Mou, Judith Olejnik, Adam J. Hume, Elke Mühlberger, Nicholas W. Lukacs, Rachel Fearns, Paul H. Lerou, Xingbin Ai
格式:	Article
語言:	英语
出版:	American Society for Clinical Investigation 2024-11-01
主題:	Infectious disease
在線閱讀:	https://doi.org/10.1172/JCI183978