Intestinal mucus-derived metabolites modulate virulence of a clade 8 enterohemorrhagic Escherichia coli O157:H7

The human colonic mucus is mainly composed of mucins, which are highly glycosylated proteins. The normal commensal colonic microbiota has mucolytic activity and is capable of releasing the monosaccharides contained in mucins, which can then be used as carbon sources by pathogens such as Enterohemorr...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Nicolás Garimano, María Luján Scalise, Fernando Gómez, María Marta Amaral, Cristina Ibarra
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Subjects:	STEC O157:H7 Shiga toxin type 2 (Stx2) intestinal mucus-derived metabolites hemolytic uremic syndrome (HUS)
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2022.975173/full