IAPP - oligomerisation levels in plasma of people with type 2 diabetes

Abstract Islet amyloid polypeptide (IAPP) is co-secreted with insulin from pancreatic ß-cells. Its oligomerisation is regarded as disease driving force in type 2 diabetes (T2D) pathology. Up to now, IAPP oligomers have been detected in affected tissues. IAPP oligomer concentrations in blood have not...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Fabian Rehn, Victoria Kraemer-Schulien, Tuyen Bujnicki, Oliver Bannach, Diethelm Tschoepe, Bernd Stratmann, Dieter Willbold
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Subjects:
IAPP
Diabetes
Disease driven protein expression
Oligomers
sFIDA
Online Access:https://doi.org/10.1038/s41598-024-70255-3

Internet

https://doi.org/10.1038/s41598-024-70255-3

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