Pathogenesis of myasthenia gravis: update on disease types, models, and mechanisms [version 1; referees: 2 approved]

Myasthenia gravis is an autoimmune disease of the neuromuscular junction (NMJ) caused by antibodies that attack components of the postsynaptic membrane, impair neuromuscular transmission, and lead to weakness and fatigue of skeletal muscle. This can be generalised or localised to certain muscle grou...

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Bibliographic Details

Published in:	F1000Research
Main Authors:	William D. Phillips, Angela Vincent
Format:	Article
Language:	English
Published:	F1000 Research Ltd 2016-06-01
Subjects:	Autoimmunity Genetics of the Immune System Leukocyte Signaling & Gene Expression Motor Systems Neurobiology of Disease & Regeneration Neuromuscular Diseases Neuronal Signaling Mechanisms
Online Access:	http://f1000research.com/articles/5-1513/v1