A liquid biopsy approach detects HCC and identifies GJA4 as a potential biomarker for HBV-HCC via plasma cfDNA methylome profiling

Abstract Background Early detection of hepatocellular carcinoma (HCC) can greatly improve the survival rate of patients. Plasma cfDNA methylation has been shown to have the potential to be a non-invasive method for diagnosing HCC. However, the identified HCC plasma cfDNA methylation sites were less...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Clinical Epigenetics
المؤلفون الرئيسيون: Jialing Sun, Xinfeng Sun, Weihuang He, Bingding Huang, Wenxing Feng, Zhiyi Han, Ruyun Ruan, Yuanke Pan, Jinxin Zhu, Jing Li, Xin Zhong, Mengqing Ma, Rui Hu, Minling Lv, Qi Huang, Wei Zhang, Mingji Feng, Jinyu Yi, Pin Cui, Xiaozhou Zhou
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2025-06-01
الموضوعات:
HBV-HCC carcinogenesis
cfDNA
Methylation profile
Early detection
DMR
الوصول للمادة أونلاين:https://doi.org/10.1186/s13148-025-01909-w

الانترنت

https://doi.org/10.1186/s13148-025-01909-w

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