Chronic intermittent hypobaric hypoxia attenuates monocrotaline-induced pulmonary arterial hypertension via modulating inflammation and suppressing NF-κB /p38 pathway

Objective(s): Inflammation is involved in various forms of pulmonary arterial hypertension (PAH). Although the pathophysiology of PAH remains uncertain, NF-κB and p38 mitogen-activated protein kinase (p38 MAPK) has been reportedto be associated with many inflammatory mediators of PAH. This study aim...

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發表在:	Iranian Journal of Basic Medical Sciences
Main Authors:	Lei Gao, Jun Liu, Yongmei Hao, Zengren Zhao, Huilian Tan, Jie Zhang, Ning Meng, Qinghou Zheng, Zhen Wang, Yi Zhang
格式:	Article
語言:	英语
出版:	Mashhad University of Medical Sciences 2018-03-01
主題:	Chronic intermittent hypobaric hypoxia Inflammation Monocrotaline NFκB Pulmonary arterial hypertension p38 MAPK
在線閱讀:	http://ijbms.mums.ac.ir/article_10192_b35277665bef3559a5f2f8fbad351a7d.pdf