Androgens and estrogens in skeletal sexual dimorphism

Bone is an endocrine tissue expressing androgen and estrogen receptors as well as steroid metabolizing enzymes. The bioactivity of circulating sex steroids is modulated by sex hormone-binding globulin and local conversion in bone tissue, for example, from testosterone (T) to estradiol (E2) by aromat...

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Bibliographic Details
Published in:Asian Journal of Andrology
Main Authors: Michaël Laurent, Leen Antonio, Mieke Sinnesael, Vanessa Dubois, Evelien Gielen, Frank Classens, Dirk Vanderschueren
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-04-01
Subjects:
androgen receptor; bone mineral density; estradiol; estrogen receptor; male; osteoblast; osteoclast; osteocyte; osteoporosis; sex hormone-binding globulin; testosterone
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=2;spage=213;epage=222;aulast=Laurent

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=2;spage=213;epage=222;aulast=Laurent

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