Dissociation of CAK from core TFIIH reveals a functional link between XP-G/CS and the TFIIH disassembly state.

Transcription factor II H (TFIIH) is comprised of core TFIIH and Cdk-activating kinase (CAK) complexes. Here, we investigated the molecular and cellular manifestation of the TFIIH compositional changes by XPG truncation mutations. We showed that both core TFIIH and CAK are rapidly recruited to damag...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Hany H Arab, Gulzar Wani, Alo Ray, Zubair I Shah, Qianzheng Zhu, Altaf A Wani
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-06-01
Online Access:	http://europepmc.org/articles/PMC2882387?pdf=render