CD22 CAR T-cell associated hematologic toxicities, endothelial activation and relationship to neurotoxicity

Background Hematologic toxicities, including coagulopathy, endothelial activation, and cytopenias, with CD19-targeted chimeric antigen receptor (CAR) T-cell therapies correlate with cytokine release syndrome (CRS) and neurotoxicity severity, but little is known about the extended toxicity profiles o...

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Bibliographic Details

Published in:	Journal for ImmunoTherapy of Cancer
Main Authors:	Hannah Smith, Haneen Shalabi, Bonnie Yates, Nirali N Shah, Hao-Wei Wang, Terry J Fry, Dong Chen, Kevin Parker, Martin Ongkeko, Yanyu Wang, Jennifer Jess, Alina Dulau-Florea, Jon Inglefield, Dan Lichtenstein, Fiorella Schischlik, Shilpa Shahani, Ann Cullinane, Eli Kane, Lauren Little, Ansuman Satpathy, Jay Lozier
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2023-06-01
Online Access:	https://jitc.bmj.com/content/11/6/e005898.full