Discrepancy between Mtb-specific IFN-γ and IgG responses in HIV-positive people with low CD4 countsResearch in context

Summary: Background: Tuberculosis (TB) is a leading infectious cause of death worldwide and treating latent TB infection (LTBI) with TB preventative therapy is a global priority. This study aimed to measure interferon gamma (IFN-γ) release assay (IGRA) positivity (the current reference standard for...

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Bibliographic Details

Published in:	EBioMedicine
Main Authors:	Maphe Mthembu, Kathryn A. Bowman, Leela R.L. Davies, Sharon Khuzwayo, Lusanda Mazibuko, Thierry Bassett, Dirhona Ramjit, Zoey Mhlane, Farina Karim, Galit Alter, Thumbi Ndung'u, Emily B. Wong
Format:	Article
Language:	English
Published:	Elsevier 2023-04-01
Subjects:	QuantiFERON assay Latent TB infection HIV CD4 count quartiles
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396423000695