Bioanalytical LC-QTOF/MS Method for a <i>N</i>-phenylpiperazine Derivate (LQFM05): An Anxiolytic- and Antidepressant-like Prototype Drug Applied to Pharmacokinetic and Biodistribution Studies

The LQFM05 is a prototype drug designed for treatment of psychiatric disorders, such as schizophrenia, exhibiting anxiolytic- and antidepressant-like (12 or 24 µmol/kg) effects in classical behavioral tests. In order to evaluate its pharmacokinetic properties, a liquid chromatography method coupled...

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書誌詳細

出版年:	Pharmaceuticals
主要な著者:	Ana Cláudia M. Ramos, Kênnia R. Rezende, Carolina M. Teixeira, Aline R. Fernandes, Heloa Santos, Rúbia Darc Machado, Ricardo Menegatti, Boniek G. Vaz, Andréa R. Chaves
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2023-06-01
主題:	antipsychotic drug LQFM05 sample pretreatment tissue distribution bioanalytical methods LC-QTOF/MS
オンライン･アクセス:	https://www.mdpi.com/1424-8247/16/7/930