del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts

We present the case of a patient with MDS RARS subtype with loss of part of the long arm of chromosome 11 del 11(q23). This a cytogenetic abnormality that occurs in 7% to 20% of RARS cases not related to poor prognosis. It seems that this deletion is a marker of iron overload in MDS.

Bibliographic Details

Published in:	São Paulo Medical Journal
Main Authors:	Maria de Lourdes Lopes Ferrari Chauffaille, José Tadeu Stéfano, Rosana Maria Valério, Maura Romeo, Maria Madalena Rodrigues, José Kerbauy
Format:	Article
Language:	English
Published:	Associação Paulista de Medicina
Subjects:	Myelodysplasia Iron overload Refractory anemia with ringed sideroblasts Karyotype
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000400010&lng=en&tlng=en