Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase.

BACKGROUND:Schistosomiasis, a severe disease caused by parasites of the genus Schistosoma, is prevalent in 74 countries, affecting more than 250 million people, particularly children. We have previously shown that the Schistosoma mansoni gut-derived cysteine peptidase, cathepsin B1 (SmCB1), administ...

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Bibliographic Details

Published in:	PLoS Neglected Tropical Diseases
Main Authors:	Hatem Tallima, Jan Dvořák, Sahira Kareem, Marwa Abou El Dahab, Nada Abdel Aziz, John Pius Dalton, Rashika El Ridi
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2017-03-01
Online Access:	http://europepmc.org/articles/PMC5386297?pdf=render