Virtual Screening and Bioassay of Novel Protoporphyrinogen Oxidase and <i>p</i>-Hydroxyphenylpyruvate Dioxygenase Dual-Target Inhibitors

Novel herbicide development is a challenge for weed control. Protoporphyrinogen oxidase (PPO) and <i>p</i>-hydroxyphenylpyruvate dioxygenase (HPPD) are two key enzymes involved in plant photosynthesis. The multi virtual screening protocol was adopted to design a common skeleton based on...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Molecules
المؤلفون الرئيسيون: Panxiu Zhang, Haifeng Cao, Tiansong Li, Ying Fu
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2025-03-01
الموضوعات:
HPPD
PPO
dual-target herbicide
skeleton-based drug discovery
Bayesian model
الوصول للمادة أونلاين:https://www.mdpi.com/1420-3049/30/7/1491

الانترنت

https://www.mdpi.com/1420-3049/30/7/1491

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