Profiling Genome-Wide DNA Methylation Patterns in Human Aortic and Mitral Valves

Cardiac valves exhibit highly complex structures and specialized functions that include dynamic interactions between cells, extracellular matrix (ECM) and their hemodynamic environment. Valvular gene expression is tightly regulated by a variety of mechanisms including epigenetic factors such as hist...

詳細記述

書誌詳細

出版年:	Frontiers in Cardiovascular Medicine
主要な著者:	Sarah Halawa, Najma Latif, Yuan-Tsan Tseng, Ayman M. Ibrahim, Adrian H. Chester, Ahmed Moustafa, Yasmine Aguib, Magdi H. Yacoub
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2022-04-01
主題:	epigenetics heart valves NOTCH signaling extracellular matrix (ECM) endothelial mesenchymal trans-differentiation (EMT) HIF-1 signaling pathway
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fcvm.2022.840647/full