Two complete 1918 influenza A/H1N1 pandemic virus genomes characterized by next-generation sequencing using RNA isolated from formalin-fixed, paraffin-embedded autopsy lung tissue samples along with evidence of secondary bacterial co-infection

ABSTRACT The 1918 influenza pandemic was the most devastating respiratory pandemic in modern human history, with 50–100 million deaths worldwide. Here, we characterized the complete genomes of influenza A virus (IAV) from two fatal cases during the fall wave of 1918 influenza A (H1N1) pandemic in th...

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Bibliographic Details

Published in:	mBio
Main Authors:	Yongli Xiao, Zong-Mei Sheng, Stephanie L. Williams, Jeffery K. Taubenberger
Format:	Article
Language:	English
Published:	American Society for Microbiology 2024-03-01
Subjects:	influenza pandemic formalin-fixed paraffin-embedded sequencing
Online Access:	https://journals.asm.org/doi/10.1128/mbio.03218-23