Prospect of targeting lysine methyltransferase NSD3 for tumor therapy

Nuclear receptor binding SET domain protein 3 (NSD3) has recently been recognized as a new epigenetic target in the fight against cancer. NSD3, which is amplified, overexpressed or mutated in a variety of tumors, promotes tumor development by regulating the cell cycle, apoptosis, DNA repair and EMT....

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Bibliographic Details

Published in:	Pharmacological Research
Main Authors:	Dan Li, Tiantian Tian, Chung-Nga Ko, Chao Yang
Format:	Article
Language:	English
Published:	Elsevier 2023-08-01
Subjects:	Epigenetic SET domain H3K36 NSD3 Cancer Anticancer
Online Access:	http://www.sciencedirect.com/science/article/pii/S1043661823001950