The Relationship between Procyanidin Structure and Their Protective Effect in a Parkinson’s Disease Model

This study evaluated the effect of grape seed-derived monomer, dimeric, and trimeric procyanidins on rat pheochromocytoma cell line (PC12) cells and in a zebrafish Parkinson’s disease (PD) model. PC12 cells were cultured with grape seed-derived procyanidins or deprenyl for 24 h and then exposed to 1...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Juan Chen, Yixuan Chen, Yangfan Zheng, Jiawen Zhao, Huilin Yu, Jiajin Zhu
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Subjects:	procyanidins Parkinson’s disease PC12 cells zebrafish Nrf2/ARE pathway
Online Access:	https://www.mdpi.com/1420-3049/27/15/5007