Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling.

Maintaining genome stability in the germline is thought to be an evolutionarily ancient role of the p53 family. The sole Caenorhabditis elegans p53 family member CEP-1 is required for apoptosis induction in meiotic, late-stage pachytene germ cells in response to DNA damage and meiotic recombination...

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Bibliographic Details

Published in:	PLoS Genetics
Main Authors:	Rachael Rutkowski, Robin Dickinson, Graeme Stewart, Ashley Craig, Marianne Schimpl, Stephen M Keyse, Anton Gartner
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-08-01
Online Access:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002238&type=printable