Limbic gray matter increases in response to cognitive-behavioral therapy in major depressive disorder

Abstract Major depressive disorder (MDD) is related to volumetric decreases in (cortico-)limbic brain regions. In contrast to pharmacological and electroconvulsive therapy, little is known about the brain structural effects of psychotherapy and potential links to symptom improvements. In a naturalis...

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Bibliographic Details
Published in:Translational Psychiatry
Main Authors: Esther Zwiky, Tiana Borgers, Melissa Klug, Philine König, Konrad Schöniger, Janine Selle, Antonia Küttner, Luisa Brunner, Elisabeth J. Leehr, Udo Dannlowski, Verena Enneking, Ronny Redlich
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Online Access:https://doi.org/10.1038/s41398-025-03545-7