DNA origami assembled spheroid for evaluating cytotoxicity and infiltration of chimeric antigen receptor macrophage (CAR-M)

Abstract Chimeric antigen receptor (CAR) T-cell therapies have shown remarkable results in patients with hematological malignancies. However, their success in treating solid tumors has been limited. As an alternative candidate for the CAR therapy, CAR-macrophages (CAR-M) have demonstrated activation...

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Bibliographic Details

Published in:	Communications Biology
Main Authors:	Qinyao Zhu, Xiaofang He, Junhua Liu, Heming Wang, Xiaojiao Shan, Guangqi Song, Luo Zhang, Yicheng Zhao, Xiushan Yin
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-10-01
Online Access:	https://doi.org/10.1038/s42003-024-07009-4