Targeting CD37 promotes macrophage-dependent phagocytosis of multiple cancer cell types and facilitates tumor clearance in mice

Abstract Macrophages play vital roles in innate and adaptive immunity, and their functions are mediated via phagocytosis and antigen presentation. Despite the effort to identify phagocytic checkpoints and explore their mechanism of action, current checkpoint-scanning strategies cannot provide a comp...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Xinya Gao, Jing Zhang, Hui Zhang, Xin Liu, Bo Zeng, Huijin Wang, Hanbing Zhang, Weng-Onn Lui, Xiaoyan Hui, Hongming Miao, Jie Li
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-07-01
Online Access:	https://doi.org/10.1038/s41467-025-61348-2