An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence.

Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms. Therefore, it is important to identify new drug targets for drug discovery and novel therapeutics. Arv1 (are1 are2 required for viability 1)...

詳細記述

書誌詳細
出版年:PLoS ONE
主要な著者: Michelle L Villasmil, Antonio Daniel Barbosa, Jessie Lee Cunningham, Symeon Siniossoglou, Joseph T Nickels
フォーマット: 論文
言語:英語
出版事項: Public Library of Science (PLoS) 2020-01-01
オンライン・アクセス:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0235746&type=printable