Prenatal methadone exposure produces functional and molecular alterations in the basolateral amygdala and decreased voluntary ethanol intake in female, but not male offspring

IntroductionA result of the ongoing opioid epidemic has been a significant rise in the rates of opioid use during pregnancy. This includes use of maintenance medications for opioid use disorder (MOUDs), such as methadone, which are the standard of care for pregnant people with an opioid use disorder...

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Bibliographic Details

Published in:	Frontiers in Behavioral Neuroscience
Main Authors:	Meredith E. Gamble, Michelle Montero, Dana N. Silberstein, Terrence Deak, Elena I. Varlinskaya, Marvin R. Diaz
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	prenatal methadone opioid basolateral amygdala ethanol stress
Online Access:	https://www.frontiersin.org/articles/10.3389/fnbeh.2025.1570951/full