Multivariate statistical modelling to improve particle treatment verification: Implications for prompt gamma-ray timing

We present an improved method for in-vivo proton range verification by prompt gamma-ray timing based on multivariate statistical modelling. To this end, prompt gamma-ray timing distributions acquired during pencil beam irradiation of an acrylic glass phantom with air cavities of different thicknesse...

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Bibliographic Details

Published in:	Frontiers in Physics
Main Authors:	Sonja M. Schellhammer, Julia Wiedkamp , Steffen Löck , Toni Kögler
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Subjects:	proton therapy treatment verification prompt gamma-ray timing machine learning multivariate modelling
Online Access:	https://www.frontiersin.org/articles/10.3389/fphy.2022.932950/full