Age-Related Gene Alteration in Naïve and Memory T cells Using Precise Age-Tracking Model

In aged individuals, age-related changes in immune cells, especially T cell deficiency, are associated with an increased incidence of infection, tumor, and autoimmune disease, as well as an impaired response to vaccination. However, the features of gene expression levels in aged T cells are still un...

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الحاوية / القاعدة:	Frontiers in Cell and Developmental Biology
المؤلفون الرئيسيون:	Xiaofeng Yang, Xin Wang, Lei Lei, Lina Sun, Anjun Jiao, Kun Zhu, Tao Xie, Haiyan Liu, Xingzhe Zhang, Yanhong Su, Cangang Zhang, Lin Shi, Dan Zhang, Huiqiang Zheng, Jiahui Zhang, Xiaobin Liu, Xiaobo Zhou, Chenming Sun, Baojun Zhang
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2021-02-01
الموضوعات:	aged T cells naïve T cells TCRδCreERR26ZsGreen mice CD4 T cells CD8 T cells
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fcell.2020.624380/full