Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis

Abstract Background Leptin is important in physiological and pathological functions in various cancers, however, the significance and mechanisms of leptin in nasopharyngeal carcinoma remain ambiguous. Methods Leptin expression was analyzed by QPCR, immunohistochemistry, Western blotting, and TCGA da...

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Bibliographic Details

Published in:	Journal of Experimental & Clinical Cancer Research
Main Authors:	Sheng-Dean Luo, Hsin-Ting Tsai, Chung-Feng Hwang, Tai‐Jan Chiu, Shau‐Hsuan Li, Ya-Ling Hsu, Chang-Chun Hsiao, Chang-Han Chen
Format:	Article
Language:	English
Published:	BMC 2022-07-01
Subjects:	Leptin NPC EGFR
Online Access:	https://doi.org/10.1186/s13046-022-02415-0