Variation in virulence between three representative Bordetella pertussis pertactin-negative clinical isolates

ABSTRACT Pertussis is a respiratory disease caused by the bacterium Bordetella pertussis. Acellular pertussis (aP) vaccines replaced more reactogenic whole-cell pertussis (wP) vaccines in the United States in the 1990s. Despite high rates of vaccination, a slow but consistent increase in the number...

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Bibliographic Details
Published in:mSphere
Main Authors: Nicole Lamond, Lindsey Zimmerman, Yihui Wang, Jonatan Maldonado Villeda, Asgeir Bjarnason, Hekla Bryndís Jóhannsdóttir, Tami H. Skoff, Maria-Lucia Tondella, Michael R. Weigand, Susan Hariri, Tod Merkel
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Subjects:
Bordetella pertussis
pertactin
immunization
baboon
Online Access:https://journals.asm.org/doi/10.1128/msphere.00310-25

Internet

https://journals.asm.org/doi/10.1128/msphere.00310-25

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