Interferon-γ from brain leukocytes enhances meningitis by type 4 Streptococcus pneumoniae

Streptococcus pneumoniae is the leading cause of bacterial meningitis. Pneumococcal meningitis is a life-threatening disease with high rates of mortality and neurological sequelae. Immune targeting of S. pneumoniae is essential for clearance of infection; however, within the brain, the induced infla...

Full description

Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Elena ePettini, Fabio eFiorino, Anna Maria Cuppone, Francesco eIannelli, Donata eMedaglini, Gianni ePozzi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-12-01
Subjects:	Meningitis Streptococcus pneumoniae murine model IFN-γ Intracranial infection TIGR4
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01340/full