Chemotherapeutic potential of betanin/capecitabine combination targeting colon cancer: experimental and bioinformatic studies exploring NFκB and cyclin D1 interplay

Introduction: Betanin (C₂₄H₂₆N₂O₁₃) is safe to use as food additives approved by the FDA with anti-inflammatory and anticancer effects in many types of cancer cell lines. The current experiment was designed to test the chemotherapeutic effect of the combination of betanin with the standard chemother...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Rehab Ahmed, Sawsan A. Zaitone, Asmaa K. K. Abdelmaogood, Huda M. Atef, Mona F. M. Soliman, Alaa M. Badawy, Howaida S. Ali, AbdelNaser Zaid, Hatem I. Mokhtar, Lamiaa M. Elabbasy, Emad Kandil, Asmaa Mokhtar Yosef, Rama I. Mahran
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Subjects:	betanin bioinformatic study capecitabine cyclin D1 experimental colon cancer mouse
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1362739/full