Validation and clinical application of a targeted next-generation sequencing gene panel for solid and hematologic malignancies

Background Next-generation sequencing (NGS) is a high-throughput technology that has become widely integrated in molecular diagnostics laboratories. Among the large diversity of NGS-based panels, the Trusight Tumor 26 (TsT26) enables the detection of low-frequency variants across 26 genes using the...

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Bibliographic Details

Published in:	PeerJ
Main Authors:	Iván Prieto-Potin, Nerea Carvajal, Jenifer Plaza-Sánchez, Rebeca Manso, Carmen Laura Aúz-Alexandre, Cristina Chamizo, Sandra Zazo, Almudena López-Sánchez, Socorro María Rodríguez-Pinilla, Laura Camacho, Raquel Longarón, Beatriz Bellosillo, Rosa Somoza, Javier Hernández-Losa, Víctor Manuel Fernández-Soria, Ricardo Ramos-Ruiz, Ion Cristóbal, Jesús García-Foncillas, Federico Rojo
Format:	Article
Language:	English
Published:	PeerJ Inc. 2020-10-01
Subjects:	Next-generation sequencing Validation Cancer Solid tumor Hematological malignancies
Online Access:	https://peerj.com/articles/10069.pdf