BRAF mutations and the association of V600E with CD133 and CDX2 expression in a Pakistani colorectal carcinoma cohort

Abstract Background Despite a high incidence of colorectal carcinoma, data regarding genetic aberrations in colorectal carcinoma (CRC) patients in Pakistan is scarce. This study aimed to determine the frequency of BRAFV600E mutations in colorectal carcinoma tissue in the Pakistani population and to...

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發表在:	BMC Cancer
Main Authors:	Sobia Hassan, Talat Mirza, Ambrina Khatoon, Uzma Bukhari, Fouzia Shaikh, Asad Karim
格式:	Article
語言:	英语
出版:	BMC 2024-09-01
主題:	Colon cancer Genetic Polymorphism Prominin-1 Cancer stem cells Vemurafenib
在線閱讀:	https://doi.org/10.1186/s12885-024-12925-z