Macrophages derived exosomes deliver miR-223 to epithelial ovarian cancer cells to elicit a chemoresistant phenotype

Abstract Background How exosomal microRNAs (miRNAs) derived from macrophages contribute to the development of drug resistance in the context of the hypoxic tumor microenvironment in epithelial ovarian cancer (EOC) remains poorly understood. Methods The miRNA levels were detected by qRT-PCR. Protein...

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書誌詳細

出版年:	Journal of Experimental & Clinical Cancer Research
主要な著者:	Xiaolan Zhu, Huiling Shen, Xinming Yin, Meiling Yang, Hong Wei, Qi Chen, Fan Feng, Yueqin Liu, Wenlin Xu, Yuefeng Li
フォーマット:	論文
言語:	英語
出版事項:	BMC 2019-02-01
主題:	Exosome miR-223 Chemoresistance Macrophages EOC
オンライン･アクセス:	http://link.springer.com/article/10.1186/s13046-019-1095-1