Investigating proteogenomic divergence in patient-derived xenograft models of ovarian cancer

Abstract Within ovarian cancer research, patient-derived xenograft (PDX) models recapitulate histologic features and genomic aberrations found in original tumors. However, conflicting data from published studies have demonstrated significant transcriptional differences between PDXs and original tumo...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Scientific Reports
المؤلفون الرئيسيون: Jesenia M. Perez, Jolene M. Duda, Joohyun Ryu, Mihir Shetty, Subina Mehta, Pratik D. Jagtap, Andrew C. Nelson, Boris Winterhoff, Timothy J. Griffin, Timothy K. Starr, Stefani N. Thomas
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Portfolio 2025-01-01
الموضوعات:
Patient-derived xenograft models (PDX)
Ovarian cancer
Proteogenomics
Mass spectrometry
Proteomics
الوصول للمادة أونلاين:https://doi.org/10.1038/s41598-024-84874-3

الانترنت

https://doi.org/10.1038/s41598-024-84874-3

مواد مشابهة