Transcriptomic time course of skeletal muscle disuse and rehabilitation in middle‐aged adults

Abstract Disuse drives rapid muscle atrophy and metabolic dysfunction. This study aimed to characterize phenotypic and transcriptomic skeletal muscle changes in middle‐aged individuals during disuse and rehabilitation. Eleven healthy middle‐aged adults (6 males, 5 females; age; 57 ± 5 years) underwe...

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Bibliographic Details

Published in:	Physiological Reports
Main Authors:	Zachary D. Von Ruff, Sean P. Kilroe, Erik D. Marchant, Emily J. Arentson‐Lantz, Steven Widen, Jill Thompson, Alejandro Villasante‐Tezanos, Elena Volpi, Doug Paddon‐Jones, Blake B. Rasmussen
Format:	Article
Language:	English
Published:	Wiley 2025-08-01
Subjects:	aging disuse atrophy resistance exercise transcriptomics
Online Access:	https://doi.org/10.14814/phy2.70497