The association of alanine aminotransferase and diabetic microvascular complications: A Mendelian randomization study

AimsAlanine aminotransferase (ALT) is positively related to diabetes risk in observational studies, whereas Mendelian randomization supports a linear causal association. In contrast, the relationship between ALT and diabetic nephropathy, and diabetic retinopathy is counter-intuitive in observational...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Yaru Bi, Yanjing Liu, Heyuan Wang, Suyan Tian, Chenglin Sun
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	alanine aminotransferase diabetic nephropathy diabetic retinopathy diabetic microvascular complication Mendelian randomization
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1104963/full