The AhR pathway is dysregulated in alopecia areata

Despite significant progress in the treatment of alopecia areata (AA), many aspects of its immune-based pathogenesis remain unexplored. IFN-γ, primarily produced by CD8+ T cells and NK cells, is considered central to AA pathogenesis. However, the complex immune signaling network contributes to thera...

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發表在:	Journal of Translational Autoimmunity
Main Authors:	Arno Belpaire, Annelies Demeyer, Elise Van Caelenberg, Nanja van Geel, Reinhart Speeckaert
格式:	Article
語言:	英语
出版:	Elsevier 2025-06-01
主題:	Alopecia areata Aryl hydrocarbon receptor Immune checkpoints IFN-γ T cells Cytotoxicity
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2589909025000176