Exploring the causal role of the immune response to varicella-zoster virus on multiple traits: a phenome-wide Mendelian randomization study

Abstract Background The immune response to infections could be largely driven by the individual’s genes, especially in the major histocompatibility complex (MHC) region. Varicella-zoster virus (VZV) is a highly communicable pathogen. In addition to infection, the reactivations of VZV can be a potent...

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Bibliographic Details
Published in:BMC Medicine
Main Authors: Xinzhu Yu, Artitaya Lophatananon, Krisztina Mekli, Kenneth R. Muir, Hui Guo
Format: Article
Language:English
Published: BMC 2023-04-01
Subjects:
Varicella- zoster virus
Anti-VZV IgG
Mendelian randomization
MR-PheWAS
MHC
Online Access:https://doi.org/10.1186/s12916-023-02843-5

Internet

https://doi.org/10.1186/s12916-023-02843-5

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