Cancer-Associated-Fibroblast-Mediated Paracrine and Autocrine SDF-1/CXCR4 Signaling Promotes Stemness and Aggressiveness of Colorectal Cancers

Colorectal cancer (CRC) is a leading cause of cancer mortality worldwide, and cancer-associated fibroblasts (CAFs) play a major role in the tumor microenvironment (TME), which facilitates the progression of CRC. It is critical to understand how CAFs promote the progression of CRC for the development...

詳細記述

書誌詳細

出版年:	Cells
主要な著者:	Chao-Yang Chen, Shih-Hsien Yang, Ping-Ying Chang, Su-Feng Chen, Shin Nieh, Wen-Yen Huang, Yu-Chun Lin, Oscar Kuang-Sheng Lee
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2024-08-01
主題:	cancer-associated fibroblasts (CAFs) stromal-derived factor-1 (SDF-1) C-X-C motif chemokine receptor 4 (CXCR4) tumor microenvironment (TME) cancer stem cells (CSCs)
オンライン･アクセス:	https://www.mdpi.com/2073-4409/13/16/1334