Ablation of ceramide synthase 2 strongly affects biophysical properties of membranes

Little is known about the effects of altering sphingolipid (SL) acyl chain structure and composition on the biophysical properties of biological membranes. We explored the biophysical consequences of depleting very long acyl chain (VLC) SLs in membranes prepared from lipid fractions isolated from a...

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Bibliographic Details

Published in:	Journal of Lipid Research
Main Authors:	Liana C. Silva, Oshrit Ben David, Yael Pewzner-Jung, Elad L. Laviad, Johnny Stiban, Sibali Bandyopadhyay, Alfred H. Merrill, Jr., Manuel Prieto, Anthony H. Futerman
Format:	Article
Language:	English
Published:	Elsevier 2012-03-01
Subjects:	ceramide sphingolipids acyl chain lipid domains tubules membrane order
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520413586